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WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6175 57682024 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6175 57682512 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6180 57684752 20. ICWP_WPSF_FeatureHandler_Base->isReadyToExecute() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:198 0.6180 57684752 21. ICWP_WPSF_FeatureHandler_Base->getProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:236 0.6180 57684752 22. ICWP_WPSF_FeatureHandler_Base->loadFeatureProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:354 Warning: include_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php on line 261 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.4004 44585656 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:327 0.4004 44586720 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.4004 44586936 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6209 57723088 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6209 57723576 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6225 57703960 20. ICWP_WPSF_FeatureHandler_Base->isReadyToExecute() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:198 0.6225 57703960 21. ICWP_WPSF_FeatureHandler_Base->getProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:236 0.6225 57703960 22. ICWP_WPSF_FeatureHandler_Base->loadFeatureProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:354 Warning: include_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php on line 261 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.4004 44585656 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:327 0.4004 44586720 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.4004 44586936 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6467 58042160 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6467 58042648 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6484 58052288 20. ICWP_WPSF_FeatureHandler_Firewall->isReadyToExecute() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:198 0.6484 58052288 21. ICWP_WPSF_FeatureHandler_Base->isReadyToExecute() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/firewall.php:15 0.6484 58052288 22. ICWP_WPSF_FeatureHandler_Base->getProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:236 0.6484 58052288 23. ICWP_WPSF_FeatureHandler_Base->loadFeatureProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:354 Warning: include_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php on line 261 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.4004 44585656 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:327 0.4004 44586720 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.4004 44586936 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6554 58367792 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6554 58368280 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6570 58382752 20. ICWP_WPSF_FeatureHandler_LoginProtect->isReadyToExecute() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:198 0.6570 58382752 21. ICWP_WPSF_FeatureHandler_Base->isReadyToExecute() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/login_protect.php:102 0.6570 58382752 22. ICWP_WPSF_FeatureHandler_Base->getProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:236 0.6570 58382752 23. ICWP_WPSF_FeatureHandler_Base->loadFeatureProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:354 Warning: require_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/login_protect.php on line 105 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.4004 44585656 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:327 0.4004 44586720 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.4004 44586936 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6554 58367792 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6554 58368280 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6591 58496080 20. ICWP_WPSF_FeatureHandler_Base->doExecuteProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:199 0.6591 58496080 21. ICWP_WPSF_Processor_LoginProtect->run() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:242 0.6592 58496160 22. ICWP_WPSF_Processor_LoginProtect->getProcessorGasp() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/login_protect.php:29 Warning: require_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/login_protect.php on line 87 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.4004 44585656 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:327 0.4004 44586720 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.4004 44586936 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6554 58367792 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6554 58368280 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6591 58496080 20. ICWP_WPSF_FeatureHandler_Base->doExecuteProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:199 0.6591 58496080 21. ICWP_WPSF_Processor_LoginProtect->run() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:242 0.6623 58665184 22. ICWP_WPSF_Processor_LoginProtect->getProcessorLoginIntent() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/login_protect.php:40 Warning: include_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php on line 261 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.4004 44585656 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:327 0.4004 44586720 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.4004 44586936 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6758 59144744 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6758 59145232 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6762 59145232 20. ICWP_WPSF_FeatureHandler_Base->isReadyToExecute() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:198 0.6762 59145232 21. ICWP_WPSF_FeatureHandler_Base->getProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:236 0.6762 59145232 22. ICWP_WPSF_FeatureHandler_Base->loadFeatureProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:354 Warning: require_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/hack_protect.php on line 81 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.4004 44585656 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:327 0.4004 44586720 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.4004 44586936 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.4281 46346184 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.4281 46346672 10. icwp_wpsf_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.4292 46434984 11. require_once('/www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php') /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-wpsf.php:52 0.4631 48898792 12. ICWP_WPSF_Shield_Security::GetInstance() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:99 0.4632 48899176 13. ICWP_Wordpress_Simple_Firewall->__construct() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:91 0.4632 48899256 14. ICWP_WPSF_Plugin_Controller->loadAllFeatures() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/init.php:27 0.5847 56398936 15. do_action() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/icwp-plugin-controller.php:1546 0.5847 56400072 16. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.5847 56400288 17. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.6758 59144744 18. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.6758 59145232 19. ICWP_WPSF_FeatureHandler_Base->onRunProcessors() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.6790 59271136 20. ICWP_WPSF_FeatureHandler_Base->doExecuteProcessor() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:199 0.6790 59271136 21. ICWP_WPSF_Processor_HackProtect->run() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/features/base.php:242 0.6791 59273088 22. ICWP_WPSF_Processor_HackProtect->runChecksumScan() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/hack_protect.php:27 0.6792 59273088 23. ICWP_WPSF_Processor_HackProtect->getSubProcessorChecksumScan() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/hack_protect.php:48 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-settings.php on line 426 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 62 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 63 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 64 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 65 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 66 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 67 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 68 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: include(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php on line 69 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.8904 67801688 6. include('/www/wordpress/blog.quotidiano.net/wp-content/themes/QN_NuHP/functions.php') /www/wordpress/blog.quotidiano.net/wp-settings.php:426 Warning: require_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/loginprotect_intent.php on line 331 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.9079 68973400 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:450 0.9079 68974456 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.9080 68974672 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.9503 69006552 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.9503 69007040 10. ICWP_WPSF_Processor_LoginProtect_Intent->onWpInit() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.9503 69007040 11. ICWP_WPSF_Processor_LoginProtect_Intent->setupLoginIntent() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/loginprotect_intent.php:24 0.9503 69007120 12. ICWP_WPSF_Processor_LoginProtect_Intent->getLoginTrack() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/loginprotect_intent.php:32 Warning: require_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/common/icwp-foundation.php on line 325 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.9079 68973400 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:450 0.9079 68974456 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.9080 68974672 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.9526 69053072 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.9526 69053560 10. wp_widgets_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.9631 69165600 11. do_action() /www/wordpress/blog.quotidiano.net/wp-includes/widgets.php:1648 0.9631 69166664 12. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.9631 69166880 13. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.9631 69168856 14. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.9632 69169344 15. ICWP_WPSF_Processor_Plugin_Badge->addPluginBadgeWidget() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.9632 69169344 16. ICWP_WPSF_Foundation::loadWpWidgets() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/plugin_badge.php:49 0.9632 69169488 17. ICWP_WPSF_Foundation::requireCommonLib() /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/common/icwp-foundation.php:172 Warning: require_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/processors/plugin_badge.php on line 50 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.9079 68973400 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:450 0.9079 68974456 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.9080 68974672 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.9526 69053072 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.9526 69053560 10. wp_widgets_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.9631 69165600 11. do_action() /www/wordpress/blog.quotidiano.net/wp-includes/widgets.php:1648 0.9631 69166664 12. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.9631 69166880 13. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.9631 69168856 14. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.9632 69169344 15. ICWP_WPSF_Processor_Plugin_Badge->addPluginBadgeWidget() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 Warning: require_once(): Unable to allocate memory for pool. in /www/wordpress/blog.quotidiano.net/wp-content/plugins/wp-simple-firewall/src/common/icwp-foundation.php on line 325 Call Stack: 0.0001 634880 1. {main}() /www/wordpress/blog.quotidiano.net/index.php:0 0.0001 635448 2. require('/www/wordpress/blog.quotidiano.net/wp-blog-header.php') /www/wordpress/blog.quotidiano.net/index.php:17 0.0008 636168 3. require_once('/www/wordpress/blog.quotidiano.net/wp-load.php') /www/wordpress/blog.quotidiano.net/wp-blog-header.php:13 0.0017 636952 4. require_once('/www/wordpress/blog.quotidiano.net/wp-config.php') /www/wordpress/blog.quotidiano.net/wp-load.php:37 0.0025 639496 5. require_once('/www/wordpress/blog.quotidiano.net/wp-settings.php') /www/wordpress/blog.quotidiano.net/wp-config.php:113 0.9079 68973400 6. do_action() /www/wordpress/blog.quotidiano.net/wp-settings.php:450 0.9079 68974456 7. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.9080 68974672 8. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.9526 69053072 9. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.9526 69053560 10. wp_widgets_init() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:0 0.9631 69165600 11. do_action() /www/wordpress/blog.quotidiano.net/wp-includes/widgets.php:1648 0.9631 69166664 12. WP_Hook->do_action() /www/wordpress/blog.quotidiano.net/wp-includes/plugin.php:453 0.9631 69166880 13. WP_Hook->apply_filters() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:310 0.9631 69168856 14. call_user_func_array() /www/wordpress/blog.quotidiano.net/wp-includes/class-wp-hook.php:286 0.9632 69169344 15. 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HOMEPAGE > Cronaca > Anticorpi monoclonali, trattamento precoce complementare al vaccino anti-Covid

Anticorpi monoclonali, trattamento precoce complementare al vaccino anti-Covid

in Cronaca, Curiosità

Gli anticorpi monoclonali già disponibili contro il Covid-19 sono il complemento ideale alla vaccinazione nei soggetti infetti con elevato rischio di progressione verso la malattia grave. Queste le conclusioni scaturite dall' analisi dei dati dei ricoveri e dei decessi per Covid-19 registrati dopo l'immissione in commercio degli anticorpi monoclonali, già approvati dall'AIFA e quindi pronti all'impiego. L'indagine è stata condotta da un gruppo di ricerca del Policlinico Federico II di Napoli, in collaborazione con la Società Italiana di Medicina Ambientale (SIMA).

Attraverso l'elaborazione dei dati è possibile quantificare i potenziali benefici derivabili da un ampio utilizzo, in maniera complementare ai vaccini, del trattamento precoce con anticorpi monoclonali negli anziani, che rappresentano la categoria più a rischio.

"Dal 2 aprile 2021 (giorno dell'approvazione degli anticorpi monoclonali) fino al 5 agosto scorso, sono stati registrati in Italia 772.502 casi ufficiali di infezione da SARS-COV-2, con una incidenza varabile da 110.594 a 5.099 casi a settimana", ha precisato Prisco Piscitelli, medico epidemiologo vicepresidente SIMA. "Di questi, circa il 10% ovvero 70.022 casi di positività riguardavano persone dai settant`anni in su, il cui peso aumentava guardando ai ricoveri ospedalieri (21.503 su 57.740) ma ancor più in termini di decessi: ben 9.963 morti erano negli over 70 sui 18.442 totali registrati nei 5 mesi dello studio".

Ivan Gentile, direttore Malattie Infettive del Policlinico Federico II, nonché coordinatore dello studio, ha appurato da parte sua che gli anticorpi monoclonali contro il virus SARS-COV-2 sono il complemento ideale alla vaccinazione nei soggetti infetti ad alto rischio di progressione verso la malattia grave. Nei primi cinque mesi dall'immissione in commercio, tuttavia, sono stati prescritti solo a 6.322 pazienti, vale a dire solo al 9% dei 70mila positivi ultrasettantenni ammalatisi da aprile ad agosto scorso. Ma c'è di più, aggiunge Gentile: "Utilizzando i dati di efficacia forniti dagli studi clinici, possiamo stimare che l'utilizzo precoce degli anticorpi monoclonali nei pazienti a rischio comporta a una netta riduzione dei ricoveri ospedalieri e dei decessi".

Secondo i calcoli degli specialisti, se almeno una parte dei 70mila ultrasettantenni che hanno contratto il coronavirus nei 5 mesi dello studio fossero stati trattati, si sarebbero evitati da 7666 a 13798 ricoveri e da 3507 fino a 6313 decessi, (in caso di terapia somministrata rispettivamente al 50% o al 90% dei settantenni positivi) con un risparmio per il Servizio sanitario nazionale stimabile tra 138 e 250 milioni di euro per la riduzione delle ospedalizzazioni, al netto del costo dei farmaci e senza contare il valore attribuibile alle vite umane salvate.

"Il vaccino rimane la risorsa chiave nella lotta al Covid-19 – commenta Alessandro Miani, presidente SIMA - ma chi si ammala va curato in maniera ottimale utilizzando tutte le armi disponibili. La nostra ricerca dimostra che gli anticorpi monoclonali sono uno strumento formidabile nella lotta al COVID ad integrazione delle vaccinazioni: vanno somministrati nei primi giorni dall'infezione perché il COVID-19 può cominciare con sintomi non severi ed essere sottovalutato, ma se si innesca la cascata infiammatoria può essere tardi".

"La proposta che inviamo al Ministero della Salute - conclude il presidente SIMA - è quella di far compilare una breve check list a tutti i soggetti che eseguono il tampone in aggiunta ai dati anagrafici che già vengono raccolti: basterebbe aggiungere agli attuali formulari una casella con le patologie che rendono il soggetto eleggibile al trattamento (diabete, cardiopatia, broncopneumopatia, immunodepressione, grave obesità) e in caso di positività avviare in maniera sistematica questi pazienti a terapia con anticorpi monoclonali presso i centri autorizzati alla somministrazione".

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