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<article class="">			<h1 class="titleBig">Tumori, terapie mirate. Domande e risposte a cura di Aiom</h1>
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			<div class="description"><p>Tumori, l'anno scorso in Italia si sono registrati 369mila nuovi casi di cancro. La sopravvivenza alla diagnosi è aumentata del 15% negli uomini e dell'8% nelle donne negli ultimi venti anni. Un obiettivo raggiunto grazie alle campagne di prevenzione e ad armi sempre più efficaci, come le <strong>terapie mirate, che colpiscono uno specifico bersaglio risparmiando le cellule sane</strong>. Per far capire ai cittadini i progressi compiuti, l'Associazione Italiana Oncologia Medica (AIOM) ha pubblicato il libro «Terapie mirate 100 domande 100 risposte», distribuita in tutti i reparti di Oncologia e scaricabile sul sito <a href="http://www.aiom.it">www.aiom.it</a>.</p>
<p>«Siamo di fronte a molecole innovative che hanno aperto un nuovo mondo non solo in termini di efficacia e attività, ma anche di qualità di vita per la bassa tossicità e la facile maneggevolezza», afferma <strong>Stefania Gori</strong>, nella foto, <strong>presidente nazionale Aiom</strong>. Il loro vantaggio principale è «l'azione selettiva che le rende potenzialmente più efficaci e meno tossiche». La target therapy è efficace solo in alcuni sottogruppi di tumori che presentano specifiche alterazioni molecolari.</p>
<p>«Queste alterazioni - precisa Gabriella Farina, direttore Dipartimento Oncologia ASST al Fatebenefratelli Sacco di Milano - sono dette anche biomarcatori e sono individuate con test che permettono di selezionare i pazienti in grado di rispondere alle terapie mirate». Ad oggi le terapie mirate sono disponibili solo per tumori come <strong>melanoma e carcinoma allo stomaco</strong> in fase avanzata, cancro <strong>alla mammella, all'ovaio, alla prostata</strong>.</p>
<p>«Anche se il numero di <strong>marcatori e relativi farmaci</strong> approvati finora è relativamente limitato - afferma Fabrizio Nicolis, presidente Fondazione Aiom - è possibile prevederne un notevole incremento nei prossimi anni, perché numerose molecole in grado di agire su specifiche alterazioni genetico-molecolari sono in sperimentazione».</p>
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